Hormones, genetics, and updates
Genes that impact hormone creation and environmental estrogen mimics
Hello everyone,
My latest article focuses on one of the genes involved in the production of steroid hormones, CYP17A1. However, this gene is just one piece of the larger puzzle in understanding how the steroid hormones are made and how they are broken down and eliminated.
In addition, I've also updated my article on BPA to explain more of the recent research on the metabolic effects of this chemical that we are all exposed to on a daily basis. I've also included new research on BPA alternatives such as BPF and BPS.
I received an email this week from a member who shared her thanks for the Genetic Lifehacks information on estrogen and the Phase II enzymes that help us break it down and eliminate it. The member sent me her recent TED talk on the topic, in case anyone is interested in learning more about hormone replacement, estrogens, and things to consider.
Coming up next week: I'm diving into the research on Lion's Mane mushroom extracts for neurogenesis.
Gratefully yours,
Debbie
CYP17A1: Steroid Hormone Production and Metabolism
Key Takeaways:
~ The formation of steroid hormones, such as testosterone and estrogen, depends on CYP17A1.
~ Genetic variants (SNPs) in the CYP17A1 gene can impact hormone levels.
~ Knowing your genetic variants can help you understand your risk for hormone-related conditions.
BPA: How Your Genes Influence BPA Detoxification
Key takeaways:
~ BPA is an endocrine disruptor similar to estrogen.
~ We are all exposed to it.
~ Individuals differ in how they break down and get rid of BPA.
What I've been reading:
1. Exploratory studies of oral and fecal microbiome in healthy human aging
Stanford study: "the composition of ... bacterial species of the healthy older group in both microbiomes was not significantly different from that of the young cohort, which suggests that dominant bacterial species are relatively stable with healthy aging."
2. Neural dysregulation in post-COVID fatigue
Long Covid "seems to result from dysregulation in specific components of the central, peripheral and autonomic nervous systems (ANSs)."
New on Long Spike:
Studies on Virus Reactivations with Covid and/or Vaccinations
Microglial Purinergic Signaling: Implications for Long COVID/Spike Neuropathology